Charles Cosby's life is changed forever when he writes a fan letter to the "Cocaine Godmother" Griselda Blanco, who is serving time in a federal prison. Six months later, Cosby is a multi-millionaire, Blanco's lover, and the head of her $40 million a year cocaine business. Also known as "The Black Widow" for her propensity to permanently dispose of her men when she's done with them, Blanco stops at nothing to ensure that Charles is faithful. Cosby soon learns he's in way over his head.