Death is just as omnipresent as ever, and in Final Destination 5 it strikes again. During the bus ride to a corporate retreat, Sam (Nicholas D'Agosto) has a premonition in which he and most of his friends as well as numerous others die in a horrific bridge collapse. When his vision ends, events begin to mirror what he had seen, and he frantically ushers as many of his colleagues including his friend, Peter (Miles Fisher), and girlfriend, Molly (Emma Bell) away from the disaster before Death can claim them. But these unsuspecting souls were never supposed to survive, and in a terrifying race against time, the ill-fated group tries to discover a way to escape Death's sinister agenda.