This otherworldly drama follows Dr. Henry Morgan (Ioan Gruffudd), a star NYC medical examiner who happens to be immortal. Only his best friend and confidant, Abe (Judd Hirsch), knows Henry's secret. Keeping that secret becomes increasingly difficult when he meets NYPD detective Jo Martinez (Alana de la Garza), who is fascinated by Henry after learning he was the sole survivor of a horrific train crash and his knowledge proves extremely helpful to her in solving crimes.