In the middle of the hippest city in America, the wild residents of 28 Barbary Lane, San Francisco are living the hi-life to the fullest! Here you'll find the bohemian best: men and women, lovers and strangers, gays and straights, all of them ready to help each other out of a jam with a quick laugh and some good (though not always legal) advice. Now their hands are REALLY full. Besides the usual delicious nights and disastrous mornings-after, our crew is facing a suicidal millionaire, a potential marriage, and one of the most notorious killers of all time!