Los Angeles, 2028: Jean "the Nurse" Thomas (Jodie Foster) runs the Hotel Artemis, a makeshift hospital that only serves criminal types. As riots grip the city, a bank robber (Sterling K. Brown) brings his wounded brother (Brian Tyree Henry) to the Artemis and is soon caught up in the wild goings-on along with a bizarre cast of characters that includes an assassin (Sofia Boutella), an arms dealer (Charlie Day), a cop (Jenny Slate), and the hotel's owner (Jeff Goldblum). Zachary Quinto co-stars in this offbeat actioner.