Susan Sarandon and Nick Nolte star in this moving, based-on-fact drama as Michaela and Augusto Odone, a couple living in the Comoro Islands whose pre-schooler son Lorenzo is stricken with ALD, a rare nerve disease that leaves him unable to move or communicate. Told by doctors that nothing can be done, the Odones refuse to give up and begin a daunting and relentless search for a cure. With Peter Ustinov, Zack O'Malley Greenburg. 129 min. Widescreen; Soundtrack: English; Subtitles: English; audio commentary; theatrical trailer.