Lose Your Head is a psycho thriller inspired by the true story of a young Portuguese man who disappeared some years ago after a night of club hopping. Like thousands of other young tourists, Luis from Madrid arrives in Berlin to spend a carefree Summer weekend. After a break-up, Berlin's infamous club scene seems the ideal place to party the pain away, make new friends and fall in love again. However, Luis resemblance to a young Greek student who had gone missing a few weeks ago gets him involved in a series of mysterious events. And what starts out like a romantic adventure turns into a desperate chase through the streets of Berlin, as Luis gets lost between paranoia and reality.