What's the best way to eat dessert? Do twins really have a psychic connection? What kind of guys are into moe girls? These are the kinds of questions that float through the inquisitive mind of anime super-fan Konata Izumi. When she's not lost in her favorite manga or logging hours in one of her online games, she's debating the mysteries of the universe with the best friends a girl could ask for. And while they might not share Konata's refined eye for anime tropes and trivia, she doesn't hold it against them. After all, Miyuki Takara is a precious moe dream girl, and twin sisters Tsukasa and Kagami are always there when she needs a helping hand or a notebook to copy homework from (even if Kagami insists on being totally tsundere about it). At the end of the day, Konata could look far and wide, but she'd never find a better group of girls to get her through the horrors of high school!