Based on the popular, cult comic book franchise of the same name, "Preacher" is a supernatural, twisted and darkly comedic drama that follows a West Texas preacher named Jesse Custer (Dominic Cooper), who is inhabited by a mysterious entity that causes him to develop a highly unusual power. Jesse, his badass ex-girlfriend Tulip (Ruth Negga) and an Irish vagabond named Cassidy (Joseph Gilgun) come together and when they do, they are thrust into a crazy world populated by a cast of characters from Heaven, Hell and everywhere in between.