Spacemen 3's second album is a remarkable departure from the band's 1986 debut, Sound Of Confusion. Reduced to a trio (guitarists / keyboardists Pete "Sonic Boom" Kember, Jason "Spaceman" Pierce, and bassist Pete Bassman) following the departure of the first album's drummer, Spacemen 3 makes an asset out of the newfound lack of percussion, giving The Perfect Prescription a considerably less rock-oriented sound with much more open space in it's varied, subtle arrangements.